Analysis of organic solvent extracts of enicostemma. Plant regeneration from the leaf explants of enicostemma. The rats received the extract, orally at the doses of 125, 250 and 500 mgkg b wtday for 21 consecutive days and ccl4, at the dose of 0. Protective effect of enicostemma littorale blume on rat model of diabetic neuropathy. Comparative phytochemical screening and antiarthritic potential in different extracts of enicostemma littorale and withania somnifera, proceedings and abstracts of international conference on multidisciplinary approaches icma 2014, university of sri jeyewardanepura, nugegoda, sri lanka, august 2014, p. Stem cylindric, glabrous with a decurrent ridge below each leaf. Pharmacognostical standardization of enicostemma littorale blume. Enicostema littorale is an herb from the plant family gentianaceae. The anti inflammatory activity of enicostemma littorale e. Sometimes this is spelled as enicostemma littorale. In vitro anti plasmodial activity of enicostemma littorale semantic. Locally it is known as chota chirayita and used in indigenous medicines in the treatment of fevers and as. Flower size was reduced significantly in the affected plants compared. The antiinflammatory activity of enicostemma littorale and mollugo.
Mar 14, 2010 diabetic nephropathy dn is one of the foremost causes of renal failure and a primary cause of diabetes mellitus related death. Methods six groups of rats were treated with ethanolic 70%vv extracts of e. We have investigated the hypolipidemic effects of swertiamarin an active lead isolated from a perennial herb enicostemma littorale blume. In developing countries, the majority of people rely on traditional medicines. Chhota chirayta enicostemma littorale ban labs pvt ltd. Hepatomodulatory role of enicostemma littorale blume. Muthiah gomathinayagam, plant growth regulation lab. Laboratory manual in biochemistry, wiley eastern ltd, new delhi 1981, p.
The content of a pharmacognosy course pdf free download. The gynoecial development inenicostemma littorale blume gentianaceae has been studied. Amelioration of stzinduced type 1 diabetic nephropathy by. Plant regeneration from the leaf explants of enicostemma littorale blume through direct organogenesis. Enicostemma littorale blume familygentianaceae a glabrous herb commonly used as a bitter tonic and substitute for swertia chirayita roxb. Niraj mukundray bhatt, suparna barua and sarita gupta. Oct 18, 2012 among them, enicostemma littorale blume e. Pharmacognostical standardization of enicostemma littorale blume the antiinflammatory activity of enicostemma littorale and mollugo cerviana. Extracts of quercetin have been used to treat or prevent diverse conditions including cardiovascular disease, hypercholesterolemia, rheumatic diseases, infections and cancer but have not been shown to be effective in clinical trials for any medical condition. Mar 22, 2019 the main objective of this study is to evaluate the antihypertrophic potential of the aqueous extract of enicostemma littorale e. Pdf phyto, physicochemical standardization of medicinal plant. Enicostema littorale is an herb found in many parts of india. Preliminary study on antifertility activity of enicostemma.
It is traditionally used as antidiabetic, urinary astringent, antiperiodic, anthelmintic, anti. Food safety theory and practice download ebook pdf, epub. Download fulltext pdf download fulltext pdf phyto, physicochemical standardization of medicinal plant enicostemma littorale, blume article pdf available march 20 with 1,618 reads. Enicostemma littorale blume on adrenaline induced hypertensive rats. Pharmacognostical standardization of enicostemma littorale.
An effective method for isolation of pure swertiamarin. Previously, we have reported that aqueous extract of enicostemma littorale has potential antidiabetic activity. In the present study an attempt has been made to develop a hptlc method for quantitative estimation of swetiamarin in plants and different marketed antidiabetic polyherbal formulations. Enicostemma littorale blume scientific monograph by amrit pal singh download pdf 21 kb. Pdf investigation of pharmacognostical and preliminary. Hence the confirmation on presence of terpenoids and its antimicrobial activity shall drive the research towards determining the cytotoxic effects of the e. Enicostemma littorale gentianaceae is also known from traditional knowledge. Diabetes mellitus is a chronic metabolic disorder characterized by hyperglycemia. Enicostemma littorale is known for its hypoglycemic activity from ancient times.
The effect of enicostemma littoraleblume on adrenalineinduced. Leaves are sessile sometimes narrowed into a petiolelike base, longer than the internodes. Pdf phyto, physicochemical standardization of medicinal. Enicostemma littorale blume is a small herb and recently we have reported its blood glucose lowering potential in alloxan induced diabetic rats. Conclusion the terpenoids were believed to contribute to. The aim of this study was to investigate the effect of enicostemma littorale gentianaceae aerial part on antioxidant defense systems of plasma and liver in p dimethylaminoazobenzene p dabinduced hepatocarcinoma in rats. Apr 25, 2018 enicostemma littorale blume, also known as mamajjaka in sanskrit, indian gentian in english and a. The bicarpellary, syncarpous gynoecium begins its development in an apocarpous fashion. Mukbaniani this volume, is designed to fulfill the requirements of scientists and engineers who wish to be.
Enicostemma littorale blume belonging to family gentianaceae. The plant was identified and authenticated by prof. Methods chloroform, methanol and acetone extracts of different parts of e. Download applied chemistry and chemical engineering, volume 5. It is found distributed throughout the greater part of india and common in coastal areas. Phytochemical and pharmacognostic value of enicostemma littorale. Enicostemma littorale prevents tumor formation in 7,12. Enicostemma littoraleblume, adrenaline, antihypertensive activity. The whole plant is used in traditional medicine for the treatment of. Traditional medicine uses cultural knowledge and practices to promote health maintenance as well as diagnose and treat disease. The method consisted of a simple step gradient from 10 to 20% ethyl acetate in n.
Current science is a fortnightly journal published since 1932 by the current science association, bangalore india in collaboration with the indian academy of sciences. This herb is also found in south america and some parts of africa. Click download or read online button to get food safety theory and practice book now. The journal covers all branches of pureapplied science and technology such as physics, chemistry, life sciences, medicine, earth sciences, engineering and technology. Glucose lowering effect of aqueous extract of enicostemma. Antiulcer and antiinflammatory activity of aerial parts enicostemma. The bittery natured plant goes about as a purgative, helps in curing fever, ailment, skin ailments, stomach issue, wind nibble, weight and controls glucose levels. Protective effect of enicostemma littorale blume methanolic extract on gentamicininduced nephrotoxicity in rats. A rapid method for the isolation of swertiamarin from enicostemma littorale. Nasal myiasis caused by cochliomyia hominivorax in the united states.
Evaluation of effect of aqueous extract of enicostemma. Haghi, ana cristina faria ribeiro, lionello pogliani, devrim balkose, francisco torrens, omari v. Enicostemma littorale blume scientific monograph core. Enicostemma littorale is a glabrous perennial herb belonging to the family. Rapid preparative isolation of erythrocentaurin from. Effect of enicostemma littorale aqueous extract on serum cholesterol and triglyceride levels in cholesterol fed rats at 6th week. It was found to be affected by a witches broom disease under the field conditions at anand, gujarat, india.
A rapid method for the isolation of swertiamarin from. Research methodologies in modern chemistry and applied science by a. Theory and practice in hospitality and tourism research includes 111 contributions from the 2nd international hospitality and tourism conference 2014 penang, malaysia, 24 september 2014, and covers a comprehensive. Cardioprotective and antihypertensive effects of enicostemma littorale blume extract in fructosefed rats. Evaluation of antihypertrophic potential of enicostemma. The free radicals and antioxidants journal aims to foster the dissemination of scientific information by publishing manuscripts. In order to download, print or access these formats you must be logged in. A hptlc method for quantitative estimation of swetiamarin in.
The plant parts like leaves and roots are used since ages in various parts of india for treating diabetes. The young carpel exhibits initial abaxial overgrowth followed by. Docking analysis was carried out for the above targets with already reported phytocompounds of enicostemma axillare syn. Stem cell therapy is one of the upcoming therapies for the treatment of diabetes. Swetiamarin is one of the phytoconstituents present in enicostemma littorale linn. Keywords enicostemma littorale type 1 diabetes nephropathy stz swertiamarin r. Erythrocentaurin is a relatively simple natural product present among the members of gentianaceae. A preparative method for the isolation of erythrocentaurin from the ethyl acetate fraction of enicostemma littorale using medium. Effect of aqueous enicostemma littorale blume extract on key carbohydrate metabolic enzymes, lipid peroxides and antioxidants in alloxaninduced diabetic rats. Pharmacognostic characterization of enicostemma littorale blume.
Effect of aqueous enicostemma littorale blume extract on. In the present study, we have investigated the effect of aqueous extract of e. Jun 26, 2012 mamejvo enicostemma axillare raynal is a perennial herb with diversified health benefits. Dose dependent hypoglycemic effect of aqueous extract of enicostemma littorale blume in alloxan induced diabetic rats. The present study investigates the effect of oral administration of an aqueous enicostemma littorale whole plant extract on some key carbohydrate metabolic enzymes and antioxidant defence in alloxaninduced diabetes in rats. Swertiamarin 50 and 75 mgkg and atorvastatin 50 mgkg was given orally daily for seven consecutive day to the high cholesterol feed. Effect of aqueous enicostemma littorale blume extract on key. Discovery of potent differentiating agents is a prerequisite for increasing islet mass. An effective method for isolation of pure swertiamarin from enicostemma littorale blume satyender kumar1, vinod jairaj 2 1 department of natural products, national institute of pharmaceutical education and research nip er ahmedabad opposite air force station, palaj, gandhinagar, gujarat 382354, india. Abstract objective to evaluate the possible antifertility activity of enicostemma axillare e. Hence, in our search for herbal remedies for diseases that require chronic treatment, we found that enicostemma littorale blume a glorious perennial herb. A rapid and reproducible protocol has been developed for in vitro regeneration of plantlets from leaf explants of enicostemma littorale blume gentianeceae. Hepatoprotective activity of enicostemma axillare in. Kadavinaya in local language, is a perennial herb of gentianaceae family.
Journal of biologically active products from nature. A small molecule swertisin from enicostemma littorale. Oral cancer is one of the most common malignancies worldwide, and india has recorded the highest annual incidence of oral cancer in comparison with other countries. Preliminary study on the antimicrobial activity of enicostemma. Volume 617, issues, 1 september 2009, pages 108112. The antiinflammatory activity of enicostemma littorale and mollugo cerviana. Enicostemma littorale methanol extract in alloxaninduced diabetic rats. Dr mrs sri ranjani sivapalan unit of siddha medicine. Nutritional composition and method for increasing creatine. Enicostemma littorale, biochemical compounds, antibacterial activity.
A hptlc method for quantitative estimation of swetiamarin. Download fulltext pdf download fulltext pdf hypolipidaemic and antioxidant effect of enicostemma littorale blume article pdf available in asian pacific journal of tropical biomedicine 15. American journal of infectious diseases science publications. Quercetin is a flavonoid found in many foods and herbs and is a regular component of a normal diet. Preliminary study on the antimicrobial activity of. Pdf hypolipidaemic and antioxidant effect of enicostemma. Free radicals and antioxidants an open access, peer. Disk diffusion method was used for antimicrobial activity and bioautography was carried out for the. This site is like a library, use search box in the widget to get ebook that you want. The present study is an attempt to screen the potential of novel small biomolecules for their differentiating property into pancreatic islet cells using nih3t3, as representative of extra pancreatic stem cells. To study detailed pharmacognostic profile and preliminary phytochemical investigation of whole plant of enicostemma littorale gentianaceae is a perennial herb found throughout india. Phytochemical and pharmacognostic value of enicostemma. Hypolipidaemic and antioxidant effect of enicostemma. Conclusion the terpenoids were believed to contribute to various medicinal properties.
The bittery natured plant acts as a laxative, helps in curing fever, rheumatism, skin diseases, abdominal disorders, snake bite, obesity and helps to regulate blood sugar levels. The free radicals and antioxidants journal aims to foster the dissemination of scientific information by publishing manuscripts that provide new insights into the biology of. Estimation of hepatic hmgco a reductase activity showed a significantly decreased activity in enicostemma littorale treated hypercholesterolemic rats. Pdf enicostemma littorale, blume gentianaceae is a glabrous perennial herb and it is found in open, sandy places among sparse. Drug consists of dried whole plant mostly root and vegetative parts of enicostemma hyssopifolium willd. Cardioprotective and antihypertensive effects of enicostemma. Mukbaniani this volume, is designed to fulfill the requirements of scientists and engineers who wish to be able to carry out experimental research in. Gynoecial ontogeny in enicostemma littorale blume springerlink. Pdf applied chemistry and chemical engineering, volume 5. Abstract full text download pdf xml views 986 downloads. The hepatomodulatory response of ethanol extract of enicostemma littorale blume was examined in contrast to oxidative stressinduced liver injury by carbon tetrachloride ccl4 in albino wistar male rats. Abstract objective to study the antimicrobial activity of enicostemma littorale e. Enzymatic and nonenzymatic antioxidant activities of.
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